Botanical names:
Aloe barbadensis, Aloe veraParts Used & Where Grown
The aloe plant originally came from Africa. The leaves, which are long, green, fleshy, and have spikes along the edges, are used medicinally. The fresh leaf gel and latex are used for many purposes. Aloe latex is the sticky residue left over after the liquid from cut aloe leaves has evapourated.
Botanical names:
Aloe barbadensis, Aloe veraHow It Works
The constituents of aloe latex responsible for its laxative effects are known as anthraquinone glycosides. These molecules are split by the normal bacteria in the large intestines to form other molecules (aglycones), which exert the laxative action. Since aloe is such a powerful laxative, other plant laxatives such as senna or cascara are often recommended first.
Topically, it is not yet clear which constituents are responsible for the wound healingproperties of aloe.23 Test tube studies suggest polysaccharides, such as acemannan, help promote skin healing by anti-inflammatory, antimicrobial, and immune-stimulating actions. Aloe’s effects on the skin may also be enhanced by its high concentration ofamino acids, as well as vitamin E, vitamin C, zinc, and essential fatty acids.
Aloe has been used to treat minor burns.24 Stabilised aloe gel is applied to the affected area of skin three to five times per day. Older case studies reported that aloe gel applied topically could help heal radiation burns,25 and a small clinical trial found it more effective than a topical petroleum jelly in treating burns.26 However, a large, modern, placebo-controlled trial did not find aloe effective for treating minor burns.27
Two small controlled human trials have found that aloe, either alone or in combination with the oral hypoglycaemic drug, glibenclamide, effectively lowers blood sugar in people with type 2 (non-insulin-dependent) diabetes.28, 29
An aloe extract in a cream has been shown effective in a double-blind trial in people with psoriasis.30
How to Use It
For constipation, a single 50–200 mg capsule of aloe latex can be taken each day for a maximum of ten days.
For minor burns, the stabilised aloe gel is applied topically to the affected area of skin three to five times per day. Treatment of more serious burns should only be done under the supervision of a healthcare professional. For internal use of aloe gel, two tablespoons (30 ml) three times per day is used by some people with conditions such as Crohn’s disease and ulcerative colitis(see precautions below). For type 2 diabetes, clinical trials have used one tablespoon (15 ml) of aloe juice, twice daily. Treatment of diabetes with aloe should only be done under the supervision of a qualified healthcare professional.
Botanical names:
Aloe barbadensis, Aloe veraInteractions with Supplements, Foods, & Other Compounds
At the time of writing, there were no well-known supplement or food interactions with this supplement.
Interactions with Medicines
Certain medicines interact with this supplement.
Botanical names:
Aloe barbadensis, Aloe veraSide Effects
Except in the rare person who is allergic to aloe, topical application of the gel is generally safe. For any burn that blisters significantly or is otherwise severe, medical attention is absolutely essential. In some severe burns and wounds, aloe gel may actually impede healing.52
The latex form of aloe should not be used by anyone with inflammatory intestinal diseases, such as Crohn’s disease, ulcerative colitis, or appendicitis. It should also not be used by children, or by women during pregnancy or breast-feeding.53
In people with constipation, aloe latex should not be used for more than ten consecutive days as it may lead to dependency and fluid loss. Extensive fluid loss may lead to depletion of important electrolytes in the body such as potassium.
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